Antioxidant activity of Rosa damascene flos ethanol extracts using hydroxyl and nitrite oxide scavenging methods

  • Elfina Br T Master Programsof Biomedical Science, Universitas Prima Indonesia, Medan, Indonesia.
  • Chrismis N G Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia.
  • Linda C Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia.
  • I Nyoman E L Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia.

Abstract

Objective: The purpose of this study were to determine antioxidant activity of Rosa damascene flos ethanol extracts.


Methods: The ethanol extracts were extracted from the crown of rose and rose base by maceration using ethanol 70% solvent. Antioxidant activity was determined with hydroxyl and nitrite oxide scavenging methods and the IC50analyzed using SPSS 23.


Results: The IC50of crown rose ethanol extract (CREE) and rose base ethanol extract (RBEE) on hydroxyl and nitrite oxide scavenging were7.61 ± 0.38μg/mL, 17.55 ± 0.37 μg/mL and were 349,57 ±0,35μg/mL, 54.93 ± 4.49 μg/mL.


Conclusions: The crown of rose ethanol extract (CREE) and rose base ethanol extract (RBEE) has activity as antioxidant.


 

Keywords: Antioxidant, Rosa damascene flos, hydroxyl, nitrite oxide.

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Author Biographies

Elfina Br T, Master Programsof Biomedical Science, Universitas Prima Indonesia, Medan, Indonesia.

Master Programsof Biomedical Science, Universitas Prima Indonesia, Medan, Indonesia.

Chrismis N G, Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia.

Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia.

Linda C, Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia.

Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia.

I Nyoman E L, Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia.

Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia.

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How to Cite
T, E., G, C., C, L., & L, I. N. (2020). Antioxidant activity of Rosa damascene flos ethanol extracts using hydroxyl and nitrite oxide scavenging methods. Asian Journal of Pharmaceutical Research and Development, 8(3), 26-28. https://doi.org/https://doi.org/10.22270/ajprd.v8i3.739