Formulation and Evaluation of New Dosage Form of Calcium and Vitamin D

  • Satish Kumar Sharma Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India
  • Anand Singh Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India
  • Anil Bhandari Pharmacy, Department of Chemistry, Jai Narain Vyas University, Jodhpur, Rajasthan, India
  • Sudhir Singh Pharmacy, Department of Chemistry, Jai Narain Vyas University, Jodhpur, Rajasthan, India

Abstract

The aim of the research work was to develop a new dosage form (tablet in tablet) of calcium and vitamin D. In this research work vitamin D3 was used as vitamin D. This type of dosage form is very useful for elder people and children who have a week swallowing reflex. They have difficulty in swallowing tablets with water. In the present research work, pre-formulated and evaluated chewable tablets of calcium and vitamin D3 (from Formulation and Evaluation of Chewable Tablets of Calcium and Vitamin D) were taken and then moulded into a jelly like material under specified conditions of temperature and humidity and a new dosage form was developed which is sweet, flavored and chewable dosage form (tablet in tablet). The new dosage form was subjected to various tests for evaluation of the new dosage form.


 

Keywords: Calcium, vitamin D, pectin, tablet in tablet.

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Author Biographies

Satish Kumar Sharma, Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Anand Singh, Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Anil Bhandari, Pharmacy, Department of Chemistry, Jai Narain Vyas University, Jodhpur, Rajasthan, India

 Pharmacy, Department of Chemistry, Jai Narain Vyas University, Jodhpur, Rajasthan, India

Sudhir Singh, Pharmacy, Department of Chemistry, Jai Narain Vyas University, Jodhpur, Rajasthan, India

 Pharmacy, Department of Chemistry, Jai Narain Vyas University, Jodhpur, Rajasthan, India

References

1. Pieste Pravina et al, Calcium and its Role in Human Body, International Journal of Research in Pharmaceutical and Biomedical Sciences, 2013;4.
2. Natasha Khazai et al, Calcium and Vitamin D; Skeltal and Extraskeltal Health NIH Public Access, 2008:10(2):110-117.
3. G. Eisenbrand, P. Schreier; ROMPP Lexikon Lebensmittelchemie; Thieme, Stuttgart; Mai 2006.
4. May, Colin D. Industrial Pectin: Sources, Production and Applications Carbohydrate Polymers.1990; 12(1):79-99.
5. Chi Chung Lin, L.E. casida, Jr: GELRITE as a gelling agent in media for the growth of thermophillic micro-organisms. Applied and Environmental Microbiology, 1984; 47:427-429.
6. Indian Pharmacopoeia; Vol II, Calcium and Vitamin D3 Tablets; 4466-4467.
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How to Cite
Sharma, S., Singh, A., Bhandari, A., & Singh, S. (2020). Formulation and Evaluation of New Dosage Form of Calcium and Vitamin D. Asian Journal of Pharmaceutical Research and Development, 8(3), 235-237. https://doi.org/https://doi.org/10.22270/ajprd.v8i3.707