Development and Evaluation of Chewable Tablets of Calcium and Vitamin D

  • Satish Kumar Sharma Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India
  • Anand Singh Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India
  • Anil Bhandari Pharmacy, Department of Chemistry, Jai Narain Vyas University, Jodhpur, Rajasthan, India
  • Sudhir Singh Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India
  • Sumer Singh Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Abstract

The aim of research work was to prepare a formulation of calcium and vitamin D chewable tablets by wet granulation method using excipients and to evaluate the tablet properties. In this research work vitamin D3 was used as vitamin D. The blend was compressed on a rotary compresson machine. Tablets were subjected to various tests (weight variation, thickness, hardness and assay of calcium and vitamin D3 etc) and the results were in compliance with the pharmacopoeial specifications. All physical properties studied indicate that all excipients are good pharmaceutical excipients for tablets. The aim of this work was to minimise the complexity of formulation and to make cost effective product. Since tablets to be prepared are chewable so sweetening and flavouring agents  are to be incorporated to make the tablet palatable and easily acceptable.


 

Keywords: Calcium, vitamin D3, wet granulation, chewable tablet, tablet formulation.

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Author Biographies

Satish Kumar Sharma, Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Anand Singh, Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Anil Bhandari, Pharmacy, Department of Chemistry, Jai Narain Vyas University, Jodhpur, Rajasthan, India

Pharmacy, Department of Chemistry, Jai Narain Vyas University, Jodhpur, Rajasthan, India

Sudhir Singh, Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Sumer Singh, Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

Research Scholar, School of Pharmacy, Singhania University, Pacheri Bari, Jhunjhunu, Rajasthan, India

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Indian Pharmacopoeia; Vol.II, Calcium and Vitamin D3 Tablets, 4466-4467.
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How to Cite
Sharma, S., Singh, A., Bhandari, A., Singh, S., & Singh, S. (2020). Development and Evaluation of Chewable Tablets of Calcium and Vitamin D. Asian Journal of Pharmaceutical Research and Development, 8(3), 232-234. https://doi.org/https://doi.org/10.22270/ajprd.v8i3.704