Evaluation of Transdermal Patches of Valproic Acid
Conventional System of Medication that requires multi dose therapy are having many problems. The controlled drug delivery is a newer approach is to deliver drug into systemic circulation. As Valproic Acid is a drug to control the manic disorder so it is necessary to maintain the concentration of drug in systemic circulation continuously. So a new approach known as transdermal drug delivery system is adopted to avoid the various drawbacks of oral and other conventional dosage form.
2. Naohiro N, Kazuhiro, T, Toshihiro S, Yoichi M. Development and evaluation of a monolithic drug-in-adhesive patch for valsartan, International Journal of Pharmaceutics, 2010, 402:103-109.
3. Parivesh S, Dqivedi S, Dwivedi A, Design, Evaluation Parameters and Marketed Produced of transdermal patches: A review, Journal of Pharmacy Research, 2010, 3(2):235-240.
4. Devi K and Paranjothi K, Development and Evaluation of Free Films and Transdermal Patches of Ketorolac Trimethamine using Polymers and Pressure Sensitive Adhesive, The Eastern Pharmacist, 1998,485:97-100.
5. Lee K, Uchida K, Kitagawa A, Gotu S: Effect of hydrophilic and lipophilic vehicles on skin permeation of tegafur, alclofenac and ibuprofen with or without permeation enharncers, Biologiacal and Pharmaceutical Bulletin, 1993, 16(12):1264-9.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).