An Updated Review of a Novel Drug Delivery System in Medicated Chewing Gum

  • Ch.Surya Kumari Pharmaceutics Research Lab, K L College of Pharmacy, Koneru Lakshmaiah Education Foundation, KL Deemed to be University, Guntur (Dt.), Andhra Pradesh-522 502, India.
  • S. Suresh Babu Department of Pharmaceutics, Vikas College of Pharmacy,Vissannapeta, Krishna (Dt.), AP 521 215.
  • Sk. Asha Begham Nimra College of Pharmacy, Nimra Nagar, Ibrahim patnam, Vijayawada, Krishna District. Pin-521456.
  • K. Venketeswerarao Department of Pharmaceutics, Vikas College of Pharmacy,Vissannapeta, Krishna (Dt.), AP 521 215.
  • G. Durgarao Department of Pharmaceutics, Vikas College of Pharmacy,Vissannapeta, Krishna (Dt.), AP 521 215.

Abstract

Chewing gums are mobile drug delivery systems. Unlike chewable tablets medicated gums are not supposed to be swallowed and may  be removed from the site of application without resort to invasive means and medicated chewing gum MCG is solid, single dose preparation. As for as patient convenience is concerned it is discrete and easy administration without water promotes higher compliance. Since it can be taken anywhere, a chewing gum formulation is an excellent choice for acute medication. The advantages for children and for patients who find swallowing tablets difficult are obvious. The medicated chewing gums are solid, single dose preparations with a base consisting mainly of gums that are intended to be chewed, but not swallowed. They contain one or more active substances, which are released by chewing and are intended to be used for local treatment of mouth diseases or systemic delivery after absorption through the buccal mucosa. This concept is supported by statements that chewing sugar free gum can help reduce the risk of dental caries (cavities). The objective of this systematic study is to appraise existing evidence concerning a possible therapeutic effect of sugar- free chewing gum for patients. MCG represents the newest system with potential uses in pharmaceuticals, over the counter medicines and neutraceuticals.


 

Keywords: Chewing gums, Mobile drug delivery system, Dental caries, Mouth diseases, Saliva.

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Author Biographies

Ch.Surya Kumari, Pharmaceutics Research Lab, K L College of Pharmacy, Koneru Lakshmaiah Education Foundation, KL Deemed to be University, Guntur (Dt.), Andhra Pradesh-522 502, India.

Pharmaceutics Research Lab, K L College of Pharmacy, Koneru Lakshmaiah Education Foundation, KL Deemed to be  University, Guntur (Dt.), Andhra Pradesh-522 502, India.

S. Suresh Babu, Department of Pharmaceutics, Vikas College of Pharmacy,Vissannapeta, Krishna (Dt.), AP 521 215.

Department of Pharmaceutics, Vikas College of Pharmacy,Vissannapeta, Krishna (Dt.), AP 521 215.

Sk. Asha Begham, Nimra College of Pharmacy, Nimra Nagar, Ibrahim patnam, Vijayawada, Krishna District. Pin-521456.

Nimra College of Pharmacy, Nimra Nagar, Ibrahim patnam, Vijayawada, Krishna District. Pin-521456.

K. Venketeswerarao, Department of Pharmaceutics, Vikas College of Pharmacy,Vissannapeta, Krishna (Dt.), AP 521 215.

Department of Pharmaceutics, Vikas College of Pharmacy,Vissannapeta, Krishna (Dt.), AP 521 215.

G. Durgarao, Department of Pharmaceutics, Vikas College of Pharmacy,Vissannapeta, Krishna (Dt.), AP 521 215.

Department of Pharmaceutics, Vikas College of Pharmacy,Vissannapeta, Krishna (Dt.), AP 521 215.

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