Potential Emphasis of Formulated Herbal Cream on Wound Healing

  • Yogesh Shivhare Sarvepalli Radhakrishnan University, Bhopal (M.P.) India
  • Alok Pal Jain Sarvepalli Radhakrishnan University, Bhopal (M.P.) India

Abstract

Aim: The present study was to formulate and evaluate the herbal cream comprising extracts of different medicinal plants.


Experimental: The aqueous extract of all selected plants (Chenopodium album, Coccinia indica, Momordica dioica, Praecitrullus fistulosus and Trichosanthes dioica) were prepared by successive solvent extraction using soxhlet apparatus. Topical herbal cream was formulate and examined on different parameters like colour, consistency, pH, viscosity, spreadability and stability. Pharmacological evaluation of formulated herbal cream was done with excision and incision wound models.


Results and Conclusion: Based on the resultant findings obtained from the different evaluation  parameters,  it  can  be  concluded  that  prepared  herbal formulation  was  stable  and  safe  to  use in wound healing activity.


 

Keywords: Excision, Incision, Evaluation, Herbal Cream

Downloads

Download data is not yet available.

Author Biographies

Yogesh Shivhare, Sarvepalli Radhakrishnan University, Bhopal (M.P.) India

Sarvepalli Radhakrishnan University, Bhopal (M.P.) India

Alok Pal Jain, Sarvepalli Radhakrishnan University, Bhopal (M.P.) India

Sarvepalli Radhakrishnan University, Bhopal (M.P.) India

References

1. Meenakshi S, Raghavan G, Virendra N, Kumar A, Shantha M. Antimicrobial, wound healing and antioxidant activity of Plagiochasma appendiculatum Lehm. Journal of Ethnopharmacology. 2006; 107:67–72.
2. Priya KS, Gnanamani A, Radhakrishnan N, Babu M. Healing potential of Datura alba on burn wounds in albino rats. Journal of Ethnopharmacology. 2002; 83:193-199.
3. Myers KA, Marshal RD, Friedin J. Principles of Pathology in Surgery, 1st edition. Blackwell Scientific Publications London. 1980; 58-82.
4. Fabio Carmona, Ana Maria, Soares Pereira. Herbal medicines: old and new concepts, truths and misunderstandings. Brazilian Journal of Pharmacognosy. 2013; 23(2):379-385.
5. Koehn FE, Carter GT. The evolving role of natural products in drug discovery. Nature Review Drug Discovery. 2005; 4 (3):206-220.
6. Raskin I, Ripoll C. Can an apple a day keep the doctor away. Current Pharmaceutical Design. 2004; 10:3419-3429.
7. Das Trailokya, Debnath Jiban, Nath Bipul, Dash Suvakanta. Formulation and evaluation of an herbal cream for wound healing activity. International Journal of Pharmacy and Pharmaceutical Sciences. 2014; 6(2):693-697.
8. Nair Sujith S, Mathew Molly, Sreena K. Formulation and Evaluation of Herbal Cream containing Curcuma longa. International Journal of Pharmaceutical and Chemical Sciences. 2012; 1(4):1362-1368.
9. Matangi Surya Prabha, Mamidi Santhosh Aruna, Gulshan MD, Raghavamma STV, Nadendla Rama Rao. Formulation and Evaluation of Anti-Aging Poly Herbal Cream. International Journal of Pharmaceutical Sciences Review and Research. 2014; 24(2):133-136.
10. Negi A, Sharma M, Singh M. Formulation and Evaluation of an Herbal Anti-Inflammatory Gel Containing Eupatorium Leaves Extract. Journal of Pharmacognosy and Phytochemistry. 2012; 1:112-117.
11. Misal G, Dixit G, Gulkarni V. Formulation and Evaluation of Herbal Gel. Indian Journal of Natural Product and Resources. 2012; 3:501-505.
12. Saha K, Mukherjee PK, Das J, Pal M, Saha BP. Wound healing activity of Leucas lavandulaefolia Rees. Journal of Ethnopharmacology. 1997; 56:139–144.
13. Ehrlich HP, Hunt TK. The Effect of Cortisone and Anabolic Steroids on the Tensile Strength of Healing Wounds. Annals of Medicine and Surgery. 1968; 57:117.
14. Kokane DD, More RY, Kale MB, Nehete MN, Mehendale PC, Gadgoli CH, Evaluation of wound healing activity of root of Mimosa pudica. Journal of Ethnopharmacology. 2009; 124:311-315.
15. Nagar Hemant Kumar, Srivastava Amit Kumar, Srivastava Rajnish, Kurmi Madan Lal, Chandel Harinarayan Singh, Ranawat Mahendra Singh. Pharmacological Investigation of the Wound Healing Activity of Cestrum nocturnum (L.) Ointment in Wistar Albino Rats. Journal of Pharmaceutics. 2016; 1-8.
Statistics
140 Views | 183 Downloads
How to Cite
Shivhare, Y., & Jain, A. (2020). Potential Emphasis of Formulated Herbal Cream on Wound Healing. Asian Journal of Pharmaceutical Research and Development, 8(1), 73-77. https://doi.org/https://doi.org/10.22270/ajprd.v8i1.639