Potential Emphasis of Formulated Herbal Cream on Wound Healing
DOI:
https://doi.org/10.22270/ajprd.v8i1.639Keywords:
Excision, Incision, Evaluation, Herbal CreamAbstract
Aim: The present study was to formulate and evaluate the herbal cream comprising extracts of different medicinal plants.
Experimental: The aqueous extract of all selected plants (Chenopodium album, Coccinia indica, Momordica dioica, Praecitrullus fistulosus and Trichosanthes dioica) were prepared by successive solvent extraction using soxhlet apparatus. Topical herbal cream was formulate and examined on different parameters like colour, consistency, pH, viscosity, spreadability and stability. Pharmacological evaluation of formulated herbal cream was done with excision and incision wound models.
Results and Conclusion: Based on the resultant findings obtained from the different evaluation parameters, it can be concluded that prepared herbal formulation was stable and safe to use in wound healing activity.
Downloads
References
2. Priya KS, Gnanamani A, Radhakrishnan N, Babu M. Healing potential of Datura alba on burn wounds in albino rats. Journal of Ethnopharmacology. 2002; 83:193-199.
3. Myers KA, Marshal RD, Friedin J. Principles of Pathology in Surgery, 1st edition. Blackwell Scientific Publications London. 1980; 58-82.
4. Fabio Carmona, Ana Maria, Soares Pereira. Herbal medicines: old and new concepts, truths and misunderstandings. Brazilian Journal of Pharmacognosy. 2013; 23(2):379-385.
5. Koehn FE, Carter GT. The evolving role of natural products in drug discovery. Nature Review Drug Discovery. 2005; 4 (3):206-220.
6. Raskin I, Ripoll C. Can an apple a day keep the doctor away. Current Pharmaceutical Design. 2004; 10:3419-3429.
7. Das Trailokya, Debnath Jiban, Nath Bipul, Dash Suvakanta. Formulation and evaluation of an herbal cream for wound healing activity. International Journal of Pharmacy and Pharmaceutical Sciences. 2014; 6(2):693-697.
8. Nair Sujith S, Mathew Molly, Sreena K. Formulation and Evaluation of Herbal Cream containing Curcuma longa. International Journal of Pharmaceutical and Chemical Sciences. 2012; 1(4):1362-1368.
9. Matangi Surya Prabha, Mamidi Santhosh Aruna, Gulshan MD, Raghavamma STV, Nadendla Rama Rao. Formulation and Evaluation of Anti-Aging Poly Herbal Cream. International Journal of Pharmaceutical Sciences Review and Research. 2014; 24(2):133-136.
10. Negi A, Sharma M, Singh M. Formulation and Evaluation of an Herbal Anti-Inflammatory Gel Containing Eupatorium Leaves Extract. Journal of Pharmacognosy and Phytochemistry. 2012; 1:112-117.
11. Misal G, Dixit G, Gulkarni V. Formulation and Evaluation of Herbal Gel. Indian Journal of Natural Product and Resources. 2012; 3:501-505.
12. Saha K, Mukherjee PK, Das J, Pal M, Saha BP. Wound healing activity of Leucas lavandulaefolia Rees. Journal of Ethnopharmacology. 1997; 56:139–144.
13. Ehrlich HP, Hunt TK. The Effect of Cortisone and Anabolic Steroids on the Tensile Strength of Healing Wounds. Annals of Medicine and Surgery. 1968; 57:117.
14. Kokane DD, More RY, Kale MB, Nehete MN, Mehendale PC, Gadgoli CH, Evaluation of wound healing activity of root of Mimosa pudica. Journal of Ethnopharmacology. 2009; 124:311-315.
15. Nagar Hemant Kumar, Srivastava Amit Kumar, Srivastava Rajnish, Kurmi Madan Lal, Chandel Harinarayan Singh, Ranawat Mahendra Singh. Pharmacological Investigation of the Wound Healing Activity of Cestrum nocturnum (L.) Ointment in Wistar Albino Rats. Journal of Pharmaceutics. 2016; 1-8.
Published
How to Cite
Issue
Section
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).