A Brief Review on Apoptosis
Keywords:
depolymerisation, cytoskeleton, chromatin condensation, necrosis, phagocytic cellAbstract
Apoptosis is a cell death mechanism characterized by depolymerization of cytoskeleton, cell shrinkage, chromatin condensation, nuclear fragmentation and translocation of phosphatidylserine to the cell surface. This process is therefore called programmed cell death. Between 50 and 70 billion cells die each day due to apoptosis in the average human adult. Apoptosis and necrosis are considered to be distinct modes of cell death; however, apoptosis can progress to secondary necrosis if apoptotic cells are not efficiently removed by phagocytic cells. During the last decade, exceptional for the basic research, the apoptosis have attracted many attentions due to its potential application in therapying the various human diseases. . In diseases caused by deficient apoptosis, such as cancer, viral latency and autoimmunity, methods of producing selective apoptosis are being sought
Downloads
Published
How to Cite
Issue
Section
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
.