Phytochemical and Antimicrobial Studies of The Crude Methanolic Extract of The Leaf of Cissus Cornifolia Baker (Planch) (Family: Vitaceae)

Authors

  • I. Atiku Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University Zaria, Nigeria
  • A. M. Musa Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University Zaria, Nigeria
  • Y. M Sani Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University Zaria, Nigeria
  • U.A Hanwa Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University Zaria, Nigeria
  • S.M Abdullahi Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University Zaria, Nigeria
  • M. I. Sule Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University Zaria, Nigeria

Keywords:

Phytochemical, antimicrobial, Cissus cornifolia

Abstract

The antimicrobial activity of the crude methanolic extracts of the leaf of Cissus cornifolia were investigated using Cup-plate and agar Diffusion methods. The extract was tested against clinical isolates of Staphylococcus aureus, Streptococcus pneumoniae, Corynebacterium ulcerans, Pseudomonas fluorescence, Proteus vulgaris and Salmonella typhi. The extract showed activities against all the organisms tested (zone of inhibition: 20-26mm) with the exception of Corynebacterium ulcerans and Pseudomonas fluorescence. Phytochemical screening of methanol extract revealed the presence of flavonoids, steroids/triterpenes, tannins and saponins. This study showed that the leaves of Cissus cornifolia contains bioactive compounds with antimicrobial activity.

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Published

2013-11-01

How to Cite

Atiku, I., Musa, A. M., Sani, Y. M., Hanwa, U., Abdullahi, S., & Sule, M. I. (2013). Phytochemical and Antimicrobial Studies of The Crude Methanolic Extract of The Leaf of Cissus Cornifolia Baker (Planch) (Family: Vitaceae). Asian Journal of Pharmaceutical Research and Development, 1(6), 79–83. Retrieved from https://ajprd.com/index.php/journal/article/view/133

Issue

Volume 1st Issue 6th Nov-Dec 2013

Section

Research Articles

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