The Current Big Thing is Really Small – A Review on Nanomaterials in Medicine with an Overview of Metal Oxide Nanomaterial Toxicity
Keywords:
Nanotechnology, nanoparticles, ROS, nanomedicine, metal oxide nanomaterials, toxicityAbstract
Nanotechnology is being employed in the pharmaceutical field for many reasons, but perhaps the leading goals are to improve drug solubility/bio-availability and/or delivery to various sites of action and development of advanced diagnostic and therapeutic devices. Among various nanomaterials, metal oxide nanomaterials have a promising application in nanomedicine. In recent years, the health impacts of nanomaterials and ultrafine particles have been paid attention. Due to a wide range of differences between the properties of nanomaterials among them and when compared to their bulk forms, there is a need to study both acute and chronic toxicities of these nanomaterials to assess their health impacts and toxicities in humans. In this review, application of nanomaterials in nano-medicine, toxicities of metal oxide nanomaterials and challenges before nano-drugs in pharmaceutical industry have been given an overview.
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